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Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis

Qian Wu, Mingyuan Zhou, Yu‐Chi Chen, Bingqi Zhu, Fangmei Zhou, Xiaoqing Ye, Yanfen Huang, Zhishan Ding

2023Journal of Ethnopharmacology28 citationsDOI

Topics & Concepts

PyroptosisARDSAlveolar macrophageHMGB1TLR4LipopolysaccharidePharmacologyInflammationProinflammatory cytokineIn vivoMacrophageChemistryMedicineBiologyIn vitroImmunologyLungBiochemistryInflammasomeInternal medicineBiotechnologyBiological and pharmacological studies of plantsPhytochemistry and Biological ActivitiesMedicinal Plants and Bioactive Compounds
Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis | Litcius