Spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors
Alireza Heidari, Ricardo Gobato
Abstract
In the current paper, spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors are investigated. Owing to its high chemical specificity and non-invasive detection capability, in the last decade, spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors has found wide application in gum cancer screening and diagnosis. In this paper, we describe recent results obtained by applying spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors to osteosarcoma and chondrosarcoma; the two main bone tumors. The results show the remarkable potential of spherical paramagnetic contribution to shielding tensor analysis of nuclear magnetic resonance signals in gum cancer cells, tissues and tumors to discriminate between subcellular components inside osteo-differentiated osteoblasts and osteosarcoma cells or; at level of tissues; to discriminate chondrogenic tumors giving the possibility to grade the level of malignancy the cartilaginous tumors under investigation.