The role of ATG16L2 in autophagy and disease
Laurence Don Wai Luu, Nadeem O. Kaakoush, Natalia Castaño‐Rodríguez
Abstract
ATG5: autophagy related 5; ATG12: autophagy related 12; ATG16L1: autophagy related 16 like 1; ATG16L2: autophagy related 16 like 2; CD: Crohn disease; IBD: inflammatory bowel diseases; IRGM: immunity related GTPase M; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; PE: phosphatidylethanolamine; RB1CC1: RB1 inducible coiled-coil 1; SLE: systemic lupus erythematosus; WIPI2B: WD repeat domain, phosphoinositide interacting 2B.
Topics & Concepts
BiologyAutophagyDiseaseCell biologyGeneticsApoptosisInternal medicineMedicineAutophagy in Disease and TherapyAdenosine and Purinergic SignalingEndoplasmic Reticulum Stress and Disease