Hydrochlorination of Alkenes with Hydrochloric Acid
Arnaud Olivier, Daniel S. Müller
Abstract
The hydrochlorination of alkenes with hydrogen chloride gas is typically limited to activated olefins. Herein, we present an innovative hydrochlorination approach utilizing hydrochloric acid within vigorously agitated solutions. Notably, the introduction of acetic acid was found to enhance the reaction rate. We substantiated the practicality of our method by conducting the hydrochlorination of styrene on a 1-mol scale with a 96% yield.
Topics & Concepts
Hydrochloric acidHydrogen chlorideAcetic acidChemistryYield (engineering)StyreneOrganic chemistryChlorinated solventsHydrogenChlorideCatalysisMaterials scienceCopolymerEngineeringGroundwaterMetallurgyPolymerGeotechnical engineeringIntracranial Aneurysms: Treatment and ComplicationsOxidative Organic Chemistry ReactionsVascular Malformations Diagnosis and Treatment