Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial
Jerry Vockley, Neal Sondheimer, Marja Puurunen, George A. Díaz, Ilona Ginevic, Dorothy K. Grange, Cary O. Harding, Hope Northrup, John A. Phillips, Shawn Searle, Janet A. Thomas, Roberto T. Zori, William S. Denney, Sharon L. Ernst, Kristina Humphreys, Nicole McWhorter, Caroline Kurtz, Aoife M. Brennan
Topics & Concepts
PhenylalanineAdverse effectMedicineClinical endpointInternal medicinePhenylketonuriasNewborn screeningPhenylalanine hydroxylaseEscherichia coliPharmacologyGastroenterologyClinical trialEndocrinologyPediatricsAmino acidBiochemistryBiologyGeneMetabolism and Genetic DisordersDiet and metabolism studiesMitochondrial Function and Pathology