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Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress

Meng Li, Shusheng Tang, Tony Velkov, Jianzhong Shen, Chongshan Dai

2024Environmental Pollution61 citationsDOI

Topics & Concepts

Unfolded protein responseEndoplasmic reticulumOxidative stressChemistryApoptosisATF4MitochondrionDownregulation and upregulationViability assayPharmacologyCell biologyGene knockdownMitochondrial fissionIn vivoIntracellularEndocrinologyInternal medicineBiologyBiochemistryMedicineBiotechnologyGeneEndoplasmic Reticulum Stress and DiseaseTrace Elements in HealthAutophagy in Disease and Therapy
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress | Litcius