Prevalence of acute appendicitis among patient admitted for acute abdomen in Ethiopia: Systematic review and meta-analysis
Mohammed Suleiman Obsa, Bulcha Guye Adema, Getahun Mola Shanka, Eyasu Alem Lake, Gedion Asnake Azeze, Robera Olana Fite
Abstract
ABSTRACT Background: Acute abdomen is an acute onset of abdominal disease entities that require immediate surgical intervention. It is one of the commonest surgical emergencies encountered both in developed and developing nations. This systemic review and meta-analysis was aimed at determining the pooled prevalence of acute appendicitis among acute abdomen patients in Ethiopia. Materials and methods: PubMed, Science Direct, Google Scholar and Excerpta Medica Database (EMBASE), AJOL, Web of Science, Mednar, and Chocrane library were searched. The data were extracted using Microsoft Excel and analyzed by using STATA version 14. Publication bias was checked by funnel plot and more objectively through Egger's regression test, with P > 0.05 considered to indicate absence publication bias. Heterogeneity of studies was checked using the I 2 test. Pooled analysis was conducted. Subgroup analysis was done by region. Leave out one sensitivity analysis was employed to see the effect of single study on the overall estimation. STATA version 14 statistical software was used for meta-analysis. Results: The overall prevalence of acute appendicitis was 44.272% (95% CI: 38.366, 50.18.503; I 2 = 93.9%). Based on the subgroup analysis, the prevalence of acute appendicitis was 53.2% in Tigrai, 46.54% in Oromia, 44.26% in SNNPR, 41.30% in Addis Ababa, and 36.81% in Amhara. Conclusion: The prevalence of acute appendicitis among acute abdomen patients is high. Therefore, close monitoring of the patient prognosis and appropriate prevention techniques is essential. Highlights: