Examining the vinyl moiety as a protecting group for hydroxyl (–OH) functionality under basic conditions
Vladimir V. Voronin, Maria S. Ledovskaya, Konstantin S. Rodygin, Valentine P. Ananikov
Abstract
A method for the protection and deprotection of alcohols <italic>via</italic> vinylation and devinylation reactions is proposed. Stability of the vinyl protecting group under various conditions is studied and synthetic applicability is demonstrated.
Topics & Concepts
ChemistryMoietyProtecting groupGroup (periodic table)Combinatorial chemistryOrganic chemistryAlkylOxidative Organic Chemistry ReactionsChemical Synthesis and ReactionsVanadium and Halogenation Chemistry