Balancing G protein selectivity and efficacy in the adenosine A2A receptor
Louis-Philippe Picard, Alexander Orazietti, Duy Phuoc Tran, Andrejs Tučs, Sari Hagimoto, Zhenzhou Qi, Shuya Kate Huang, Koji Tsuda, Akio Kitao, Adnan Sljoka, R. Scott Prosser
Topics & Concepts
Adenosine A2A receptorChemistryAdenosineG protein-coupled receptorAdenosine receptorSelectivityReceptorCell biologyPharmacologyBiochemistryComputational biologyBiologyCatalysisAgonistAdenosine and Purinergic SignalingReceptor Mechanisms and SignalingPancreatic function and diabetes