Microspheres as A Novel Drug Delivery System - A Review
K. S Athira, K Vineetha, Krishnananda Kamath K, A R Shabaraya
Abstract
Controlled drug delivery system can conquer the issues of conventional drug therapy and gives better therapeutic efficacy of a drug. The microspheres are one of the novel drug delivery system which can be given as an effective therapeutic alternative to conventional or immediate release single-unit dosage forms. Microspheres are spherical free flowing powder having particle size less than 200μm, consisting of synthetic polymers and proteins which are biodegradable in nature. Microsphere improves bioavailability, reduces the side effects, improves stability, decreases dose frequency and targets the drug to specific site at predetermined rate. The different types of microspheres are bioadhesive, floating, radioactive, polymeric and biodegradable microspheres. In future microspheres will track down the focal spot in novel drug delivery conveyance, especially in diagnostics, genetic materials, targeted and effective drug delivery.