A benzimidazole-based ratiometric fluorescent probe for the accurate and rapid monitoring of lysosomal pH in cell autophagy and anticounterfeiting
Chaochao Wen, Jinyin Ge, Yu Huang, Tao Gong, Congying Wang, Baofeng Yu, Wenting Liang
Abstract
The lysosomal targeted ratiometric fluorescent BD probe reveals excellent application performance in the fields of selective monitoring of the lysosome pH of living cells, real-time dynamic monitoring of autophagy, and document anti-counterfeiting.
Topics & Concepts
AutophagyFluorescenceChemistryBenzimidazoleImidazoleMoietyLysosomeBiocompatibilityCellLive cell imagingBiophysicsSelectivityStokes shiftCombinatorial chemistryBiochemistryStereochemistryApoptosisCatalysisBiologyOrganic chemistryPhysicsEnzymeQuantum mechanicsAdenosine and Purinergic SignalingAutophagy in Disease and TherapyDendrimers and Hyperbranched Polymers