Tanshinone IIA Improves Depression-like Behavior in Mice by Activating the ERK-CREB-BDNF Signaling Pathway
Jiaqi Lü, Hang Zhou, Danyang Meng, Junjun Zhang, Kailing Pan, Bo Wan, Zhigang Miao
Topics & Concepts
CREBBehavioural despair testTail suspension testMAPK/ERK pathwayNeurotrophic factorsNeuroprotectionSalvia miltiorrhizaHippocampusBrain-derived neurotrophic factorEndocrinologyPharmacologyAntidepressantInternal medicineChemistryMedicineKinaseTranscription factorReceptorBiochemistryTraditional Chinese medicineAlternative medicineGenePathologyNerve injury and regenerationNeuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms