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Generalization—a key challenge for responsible AI in patient-facing clinical applications

Lea Goetz, Nabeel Seedat, Robert Vandersluis, Mihaela van der Schaar

2024npj Digital Medicine103 citationsDOIOpen Access PDF

Abstract

Generalization – the ability of AI systems to apply and/or extrapolate their knowledge to new data which might differ from the original training data – is a major challenge for the effective and responsible implementation of human-centric AI applications. Current debate in bioethics proposes selective prediction as a solution. Here we explore data-based reasons for generalization challenges and look at how selective predictions might be implemented technically, focusing on clinical AI applications in real-world healthcare settings.

Topics & Concepts

GeneralizationKey (lock)Computer scienceArtificial intelligenceBioethicsMachine learningData scienceHealth careComputer securityPolitical scienceEpistemologyPhilosophyLawArtificial Intelligence in Healthcare and EducationExplainable Artificial Intelligence (XAI)Clinical Reasoning and Diagnostic Skills
Generalization—a key challenge for responsible AI in patient-facing clinical applications | Litcius