Molecular insights into the inhibition of early stages of Aβ peptide aggregation and destabilization of Alzheimer's Aβ protofibril by dipeptide D-Trp-Aib: A molecular modelling approach
Ali Abdulmawjood Mohammed, Sagar S. Barale, Subodh Ashok Kamble, Sneha B. Paymal, Kailas D. Sonawane
Topics & Concepts
ChemistryFibrilMonomerMolecular dynamicsBiophysicsDipeptidePeptideBeta sheetHydrophobic effectCrystallographyStereochemistryBiochemistryComputational chemistryOrganic chemistryBiologyPolymerAlzheimer's disease research and treatmentsBiochemical effects in animalsProtein Structure and Dynamics