Assessing the Prevalence of Astroviruses in Water Environments: A Systematic Review and Meta-analysis
Guy Roussel Takuissu, Sébastien Kenmoe, Jean Thierry Ebogo‐Belobo, Cyprien Kengne-Ndé, Donatien Serge Mbaga, Arnol Bowo‐Ngandji, Juliette Laure Ndzie Ondigui, Raoul Kenfack‐Momo, Serges Tchatchouang, Josiane Kenfack‐Zanguim, Robertine Lontuo Fogang, Elisabeth Zeuko’o Menkem, Ginette Irma Kame‐Ngasse, Jeannette Nina Magoudjou‐Pekam, Vito Martella, Carolina Veneri, Pamela Mancini, Giusy Bonanno Ferraro, M. Iaconelli, Elisabetta Suffredini, Giuseppina La Rosa
Abstract
Astroviruses (AstVs) are a major cause of gastroenteritis, especially in children. They can be transmitted through various pathways, including environmental contamination via water matrices. This study aimed to investigate the prevalence of AstV in different types of water, such as untreated and treated wastewater, surface water (e.g., rivers, lakes, and seawater), groundwater, drinking water, and other water matrices (e.g., irrigation water, gray water, reservoir water, floodwater, and pig slaughterhouse effluents). The meta-analysis included 80 articles, and the overall prevalence of AstV in water matrices was 36.6% [95% confidence interval (CI) of 29.6-44.0]. The highest prevalence was found in untreated wastewater at 56.8% (95% CI of 41.5-71.5), followed by treated wastewater at 48.5% (95% CI of 30.6-66.5), surface water at 28.6% (95% CI of 21.1-36.7), other matrices at 9.8% (95% CI of 0.7-25.3), drinking water at 3.3% (95% CI of 0.2-8.7), and groundwater at 0.5% (95% CI of 0.0-3.4). The most frequent AstVs detected in water environments were human AstVs, but canine and feline AstVs were also detected. Our findings highlight the importance of water as a potential route for AstV transmission, even in high-income countries. Effective water surveillance and treatment measures are necessary to minimize AstV environmental circulation and human infection through water.