Inhibition of CYP3A4 enhances aloe-emodin induced hepatocyte injury
HU Yinghuan, Zhengyang Quan, Dengke Li, Chengyu Wang, Zhenxiao Sun
Topics & Concepts
CYP3A4HepatocyteReactive oxygen speciesLiver injuryApoptosisPharmacologyChemistryMicrosomeHepatoprotectionEmodinAloe emodinCytochrome P450Oxidative stressBiochemistryEnzymeBiologyGlutathioneIn vitroPhytochemistry and biological activity of medicinal plantsBiological and pharmacological studies of plantsGinseng Biological Effects and Applications