Versatile Therapeutic Values of N‐Containing Heterocycles Benzimidazole, Piperazine and Piperidine Hybrids
Ajayrajsinh R. Zala, Premlata Kumari
Abstract
Abstract Nitrogen‐containing benzimidazole, piperazine, and piperidine are significant pharmacophores in medicinal chemistry and drug development. Many medications, lead compounds, and various reagents have these N‐containing scaffolds. This review concentrated on the development of novel therapeutic agents as well as the broad range of pharmacological actions demonstrated by benzimidazole, piperazine, and piperidine hybrids. The review emphasizes these hybrids′ potential, range, and medical significance. The review also discusses the structural criteria for benzimidazole, piperazine, and piperidine hybrids created by diverse chemists to be physiologically effective against a variety of disorders.
Topics & Concepts
PiperazinePiperidineBenzimidazolePharmacophoreChemistryCombinatorial chemistryPharmacologyBiologyOrganic chemistryStereochemistrySynthesis and biological activitySynthesis and Biological EvaluationQuinazolinone synthesis and applications