Integrative analyses of bulk and single-cell RNA-seq identified cancer-associated fibroblasts-related signature as a prognostic factor for immunotherapy in NSCLC
Shasha Wang, Guangyu Fan, Lin Li, Yajun He, Ning Lou, Tongji Xie, Liyuan Dai, Ruyun Gao, Mengwei Yang, Yuankai Shi, Xiaohong Han
Topics & Concepts
Tumor microenvironmentImmunotherapyCancer researchCarcinogenesisCancer-Associated FibroblastsTranscriptomeBiologyImmune systemMesenchymal stem cellGene signatureEpithelial–mesenchymal transitionCancerOncologyMetastasisGene expressionMedicineImmunologyGeneCell biologyGeneticsFerroptosis and cancer prognosisImmune cells in cancerCancer Immunotherapy and Biomarkers