Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias
Chun Hu, Carlos A. Leche, Anatoly Kiyatkin, Zhaolong Yu, Steven E. Stayrook, Kathryn M. Ferguson, Mark A. Lemmon
Topics & Concepts
EpiregulinEpidermal growth factor receptorEpidermal growth factorExtracellularTyrosine kinaseMutationCancer researchChemistryBiologySignal transductionCell biologyReceptorBiochemistryGeneAmphiregulinLung Cancer Treatments and MutationsCancer therapeutics and mechanismsHER2/EGFR in Cancer Research