Aeromonas hydrophila Induces Skin Disturbance through Mucosal Microbiota Dysbiosis in Striped Catfish ( <i>Pangasianodon hypophthalmus</i> )
Li-Hsuan Chen, Chia-Hsuan Lin, Ru-Fang Siao, Liang‐Chun Wang
Abstract
The fish skin mucosal microbiota is essential in modulating the host response to the presence of pathogens. Our study provides a platform to study both the correlation and causation of the interactions among the pathogen, fish skin, and the skin mucosal microbiota. Based on these findings, we provide the first mechanistic information on how mucosal microbiota changes induced by the pathogen AH result in skin disturbance with immune stimulation in striped catfish in the natural state and a potential direction for early-infection screening. Thus, this study is highly significant in the prevention of fish disease.
Topics & Concepts
BiologyMucusMicrobiologyPathogenDysbiosisImmune systemAeromonas hydrophilaCatfishCommensalismImmunologyAeromonasGut floraBacteriaFish <Actinopterygii>EcologyFisheryGeneticsAquaculture disease management and microbiotaVibrio bacteria research studiesGut microbiota and health