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miR-142 downregulation alleviates the impairment of spatial learning and memory, reduces the level of apoptosis, and upregulates the expression of pCaMKII and BAI3 in the hippocampus of APP/PS1 transgenic mice

Chang-Hai Fu, Xueyan Han, Lei Tong, Peng-Yin Nie, Yuedong Hu, Li-Li Ji

2021Behavioural Brain Research22 citationsDOI

Topics & Concepts

HippocampusDownregulation and upregulationSynapsin IGenetically modified mouseTransgeneBiologyCell biologyAlzheimer's diseaseNeurosciencemicroRNAHippocampal formationNeuroprotectionInternal medicineMedicineDiseaseBiochemistryGeneMembraneVesicleSynaptic vesicleAlzheimer's disease research and treatmentsNuclear Receptors and SignalingMicroRNA in disease regulation
miR-142 downregulation alleviates the impairment of spatial learning and memory, reduces the level of apoptosis, and upregulates the expression of pCaMKII and BAI3 in the hippocampus of APP/PS1 transgenic mice | Litcius