Design, synthesis, and biological evaluation of tetrahydroisoquinoline based hydroxamate derivatives as HDAC 6 inhibitors for cancer therapy
Yogesh Mahadu Khetmalis, Bakhya Shree, Boddupalli Venkata Siva Kumar, Markus Schweipert, Cécile Debarnot, Ashna Fathima, Sankaranarayanan Murugesan, Jamma Trinath, Vivek Sharma, Franz‐Josef Meyer‐Almes, Kondapalli Venkata Gowri Chandra Sekhar
Topics & Concepts
ChemistryHDAC8TetrahydroisoquinolineHydroxamic acidHistone deacetylaseStereochemistryCancer cellCancerCell cultureBiochemistryHistoneGeneGeneticsInternal medicineBiologyMedicineHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis