Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen

Eleanor Jing Yi Cheong, Pramod C. Nair, Rebecca Wan Yi Neo, Thanh Tu Ho, Fu Lin, Edmund Chiong, Kesavan Esuvaranathan, Hao Fan, Russell Z. Szmulewitz, Cody J. Peer, William D. Figg, Christina L. L. Chai, John O. Miners, Eric Chun Yong Chan