Polystyrene nanoplastics accumulate in ZFL cell lysosomes and in zebrafish larvae after acute exposure, inducing a synergistic immune response <i>in vitro</i> without affecting larval survival <i>in vivo</i>
I. Brandts, Marlid Garcia-Ordoñez, Lluís Tort, Mariana Teles, Nerea Roher
Abstract
Polystyrene nanoplastics are internalized in zebrafish liver cells, accumulating in lysosomes, and in zebrafish larvae but do not affect the larval suvival to a lethal infection.
Topics & Concepts
ZebrafishLarvaIn vivoImmune systemCell biologyIn vitroBiologyCellImmunologyEcologyBiochemistryGeneBiotechnologyMicroplastics and Plastic PollutionRNA Interference and Gene DeliveryNanoparticles: synthesis and applications