N‐Heterocyclic Carbene‐Catalyzed Activation of 3‐Membered Rings: Cyclopropanes, Epoxides, Azirines and Aziridines
Xiaoqun Yang, Yi Zhang, Tingting Li, Zhichao Jin
Abstract
Abstract The activations of carbonyl compounds bearing cyclopropyl, epoxyl, azirine and aziridinyl groups by N‐heterocyclic carbene (NHC) organic catalysts are reviewed. The reactions are introduced and discussed from 3 aspects according to the activation modes involved in these transformations. A brief summary on the achievements and the remaining challenges in NHC‐catalyzed activation of cyclopropanes and their analogues is given at the end of this minireview. Our own perspectives on the future development within this highly active research field are also provided.
Topics & Concepts
CarbeneChemistryCatalysisRing (chemistry)Organic chemistryCombinatorial chemistryStereochemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCyclopropane Reaction MechanismsCatalytic C–H Functionalization Methods