Integrative analysis of ultra-deep RNA-seq reveals alternative promoter usage as a mechanism of activating oncogenic programmes during prostate cancer progression
Meng Zhang, Martin Sjöström, Xiekui Cui, Adam Foye, Kyle Kai‐How Farh, Raunak Shrestha, Arian Lundberg, Ha X. Dang, Haolong Li, Phillip G. Febbo, Rahul Aggarwal, Joshi J. Alumkal, Eric J. Small, The SU2C/PCF West Coast Prostate Cancer Dream Team, Rahul Aggarwal, Joshi J. Alumkal, Felix Y. Feng, Adam Foye, David A. Quigley, Eric J. Small, Christopher A. Maher, Felix Y. Feng, David A. Quigley
Topics & Concepts
Prostate cancerFOXA1Cancer researchPromoterBiologyAndrogen receptorTranscription factorProstateDNA methylationGeneChromoplexyRegulation of gene expressionEpigeneticsCancerGene expressionGeneticsPCA3Prostate Cancer Treatment and ResearchCancer-related molecular mechanisms researchRNA Research and Splicing