Epitope-based minigene vaccine targeting fibroblast activation protein α induces specific immune responses and anti-tumor effects in 4 T1 murine breast cancer model
Fang-Fang Zhang, Yaru Qiao, Yu Xie, Chenlu Liu, Hui Wu, Jiaxin Wu, Xianghui Yu, Wei Kong, Haihong Zhang
Topics & Concepts
EpitopeImmunogenicityMinigeneImmune systemAntigenImmunotherapyCancer immunotherapyCTL*Cancer researchImmunologyCancer vaccineBiologyFibroblast activation protein, alphaTumor microenvironmentMedicineCancerInternal medicineRNACD8BiochemistryGeneRNA splicingPeptidase Inhibition and AnalysisUbiquitin and proteasome pathwaysAntimicrobial Peptides and Activities