Oxysophocarpine suppresses FGFR1-overexpressed hepatocellular carcinoma growth and sensitizes the therapeutic effect of lenvatinib
Zhongwei Zhao, Jingjing Song, Dengke Zhang, Fazong Wu, Jianfei Tu, Jiansong Ji
Topics & Concepts
LenvatinibCancer researchCell growthFibroblast growth factor receptor 1MedicineProtein kinase BMAPK/ERK pathwayApoptosisPI3K/AKT/mTOR pathwayHepatocellular carcinomaSignal transductionInternal medicineSorafenibReceptorBiologyFibroblast growth factorCell biologyBiochemistryFibroblast Growth Factor ResearchProteoglycans and glycosaminoglycans researchLiver physiology and pathology