Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition
Gilles van Tienderen, Oskar Rosmark, Ruby Lieshout, Jorke Willemse, Floor de Weijer, Linda Elowsson, Gunilla Westergren‐Thorsson, Michail Doukas, Bas Groot Koerkamp, Martin E. van Royen, Luc J. W. van der Laan, Monique M.A. Verstegen
Topics & Concepts
Extracellular matrixDecellularizationOrganoidDesmoplasiaCell biologyTumor microenvironmentIn vivoEpithelial–mesenchymal transitionBasement membraneTissue engineeringCollagen VICancer researchBiologyBiomedical engineeringStromaDownregulation and upregulationTumor cellsImmunologyMedicineImmunohistochemistryBiochemistryBiotechnologyGeneTissue Engineering and Regenerative MedicineCholangiocarcinoma and Gallbladder Cancer StudiesMedical Imaging and Pathology Studies