Rationally designed highly amphipathic antimicrobial peptides demonstrating superior bacterial selectivity relative to the corresponding α-helix peptide
Jingying Zhang, Anqi Chu, Xu Ouyang, Beibei Li, Ping Yang, Zufang Ba, Yinyin Yang, Wenbo Mao, Chao Zhong, Sanhu Gou, Yun Zhang, Hui Liu, Jingman Ni
Topics & Concepts
ChemistryPeptideAmphiphileSelectivityAntimicrobialCombinatorial chemistryAntimicrobial peptidesStereochemistryAntibacterial agentBiochemistryOrganic chemistryAntibioticsPolymerCopolymerCatalysisAntimicrobial Peptides and ActivitiesBiochemical and Structural CharacterizationChemical Synthesis and Analysis