Improved batch and flow syntheses of the nonsteroidal anti-inflammatory COX-2 inhibitor celecoxib
Chantal Scholtz, Darren L. Riley
Abstract
The comparison of an improved conventional batch mode synthesis of the nonsteroidal anti-inflammatory COX-2 inhibitor celecoxib with its flow chemistry alternative is reported.
Topics & Concepts
CelecoxibNonsteroidalCOX-2 inhibitorChemistryAnti-inflammatoryPharmacologyMedicineCyclooxygenaseBiochemistryEnzymeInnovative Microfluidic and Catalytic Techniques InnovationSynthesis of β-Lactam CompoundsChemical Synthesis and Analysis