A ferroptosis amplifier based on triple-enhanced lipid peroxides accumulation strategy for effective pancreatic cancer therapy
Mengyao Chen, Xiaohan Tong, Yanting Sun, Chunyan Dong, Chen Li, Chunhui Wang, Minyi Zhang, Yixuan Wen, Pei Ye, Ruihao Li, Jie Wan, Shujing Liang, Shuo Shi
Topics & Concepts
GPX4Lipid peroxidationReactive oxygen speciesCancer researchGlutathionePancreatic cancerTumor microenvironmentCancer cellAutophagyCell biologyChemistryApoptosisGlutathione peroxidaseMaterials scienceBiochemistryOxidative stressCancerBiologyMedicineInternal medicineEnzymeTumor cellsFerroptosis and cancer prognosisNanoplatforms for cancer theranosticsImmune cells in cancer