Litcius/Paper detail

LINC00857 Interacting with YBX1 to Regulate Apoptosis and Autophagy via MET and Phosphor-AMPKa Signaling

Wenmei Su, Lihui Wang, Huijie Zhao, Shengmin Hu, Yi Zhou, Chunfang Guo, Bin Wu, Lixia Li, Zhixiong Yang, David G. Beer, Guoan Chen

2020Molecular Therapy — Nucleic Acids57 citationsDOIOpen Access PDF

Abstract

YBX1-MET/p-AMPKa signaling is critical to regulate cell proliferation, apoptosis, and autophagy, which may provide a potential clinically therapeutic target in lung cancer.

Topics & Concepts

Gene silencingCancer researchAutophagyCell growthKRASBiologyDownregulation and upregulationGene knockdownLung cancerCellCell biologyCancerApoptosisMedicineColorectal cancerPathologyGeneGeneticsCancer-related molecular mechanisms researchRNA modifications and cancerRNA Research and Splicing