Uncontrolled transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of Cryptococcus neoformans
Shelby Priest, Vikas Yadav, Cullen Roth, Tim A. Dahlmann, Ulrich Kück, Paul M. Magwene, Joseph Heitman
Topics & Concepts
Cryptococcus neoformansDrug resistanceCryptococcosisBiologyAntifungal drugTransposition (logic)MicrobiologyAntifungalSomatic hypermutationRNA interferenceCryptococcusVirologyDrugGeneticsGenePharmacologyRNAAntibodyB cellLinguisticsPhilosophyFungal Infections and StudiesCytomegalovirus and herpesvirus researchPlant and Fungal Interactions Research