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TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

Li Zhong, Xuan Sheng, Wanbing Wang, Yanzhong Li, Rengong Zhuo, Kai Wang, Lianshuai Zhang, Dandan Hu, Yujuan Hong, Linting Chen, Hengjun Rao, Tingting Li, Muyang Chen, Zhihao Lin, Yun‐wu Zhang, Xin Wang, Xiao‐Xin Yan, Xiaochun Chen, Xiaochun Chen, Guojun Bu, Xiao‐Fen Chen, Xiao‐Fen Chen

2023Immunity153 citationsDOIOpen Access PDF

Topics & Concepts

NeurodegenerationComplement (music)BiologyComplement receptorComplement systemNeuroscienceTREM2Complement C1qReceptorCell biologyImmunologyMicrogliaImmune systemInflammationBiochemistryDiseaseMedicineInternal medicinePhenotypeComplementationGeneNeuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysComplement system in diseases
TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration | Litcius