A population pharmacokinetic model of polymyxin B based on prospective clinical data to inform dosing in hospitalized patients
Patrick O. Hanafin, Andrea Lay‐Hoon Kwa, Alexandre Prehn Zavascki, Ana Maria Sandri, Marc H. Scheetz, Christine J. Kubin, Jayesh Shah, Benjamin Pei Zhi Cherng, Michael T. Yin, Jiping Wang, Lu Wang, David P. Calfee, Maureen Bolon, Jason M. Pogue, Anthony W. Purcell, Roger L. Nation, Jian Li, Keith S. Kaye, Gauri G. Rao
Topics & Concepts
DosingPolymyxin BMedicinePharmacokineticsVolume of distributionPopulationRenal functionCmaxCreatinineInternal medicineAntibioticsChemistryBiochemistryEnvironmental healthAntibiotic Resistance in BacteriaPneumocystis jirovecii pneumonia detection and treatmentAntibiotics Pharmacokinetics and Efficacy