The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022
Saranya Sridhar, Roman M. Chicz, William H. Warren, Jim Tartaglia, Stephen J. Savarino, Sanjay Gurunathan, Jean‐François Toussaint
Abstract
Currently approved COVID vaccines are designed using the spike antigen derived from the ancestral strain, but health authorities are recommending changes to the vaccine strain to combat emerging variants. The goal is to ensure that next generation vaccines can tackle multiple variants of concern including the most prevalent variant for the coming season. We here discuss recent preclinical and clinical data on COVID vaccine antigens that are potential candidates for an updated vaccine.
Topics & Concepts
Booster (rocketry)Coronavirus disease 2019 (COVID-19)VirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakAntigenComputational biologyMedicineBiologyImmunologyInfectious disease (medical specialty)DiseaseOutbreakPhysicsAstronomyPathologySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesViral gastroenteritis research and epidemiology