The role of HER2 alterations in clinicopathological and molecular characteristics of breast cancer and HER2-targeted therapies: a comprehensive review
Shafighe Asgari-Karchekani, Armin Aryannejad, Seied Asadollah Mousavi, Shirin Shahsavarhaghighi, Seyed Mohammad Tavangar
Topics & Concepts
Breast cancerMedicineCancerReceptor tyrosine kinaseCancer researchMalignancyOncologyInternal medicineTrastuzumabTargeted therapyLapatinibEpidermal growth factor receptorPI3K/AKT/mTOR pathwayHematologyBiologyReceptorSignal transductionGeneticsHER2/EGFR in Cancer ResearchAdvanced Breast Cancer TherapiesMonoclonal and Polyclonal Antibodies Research