Discovery of potential novel CRBN modulators by virtual screening and bioassay
Feng Xiong, Lingmei Kong, Liang Chen, Minggao Xue, Feng Cao, Shuqun Zhang, Hongmei Li, Hui Yan, Yan Li, Zhili Zuo
Topics & Concepts
CereblonChemistryUbiquitin ligaseApoptosisCell biologyCancer researchUbiquitinBiochemistryBiologyGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and Disease