An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
Julian Nüchel, Marina Tauber, Janica L. Nolte, Matthias Mörgelin, Clara Türk, Beate Eckes, Constantinos Demetriades, Markus Plomann
Topics & Concepts
BiologymTORC1Cell biologyGolgi apparatusSecretionProteomeCrosstalkProteostasisPhosphorylationSecretory pathwaySignal transductionEndoplasmic reticulumBioinformaticsPI3K/AKT/mTOR pathwayBiochemistryOpticsPhysicsCellular transport and secretionEndoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathways