Assessment <i>In Vitro</i> of the Antimalarial and Transmission-Blocking Activities of Cipargamin and Ganaplacide in Artemisinin-Resistant <i>Plasmodium falciparum</i>
Achaporn Yipsirimetee, Pornpawee Chiewpoo, Rupam Tripura, Dysoley Lek, Nicholas Day, Arjen M. Dondorp, Sasithon Pukrittayakamee, Nicholas J. White, Kesinee Chotivanich
Abstract
Artemisinin resistance in Plasmodium falciparum has emerged and spread widely in the Greater Mekong Subregion, threatening current first-line artemisinin combination treatments. New antimalarial drugs are needed urgently.
Topics & Concepts
GametocytePlasmodium falciparumArtemisininArtesunateBiologyMalariaVirologyPharmacologyImmunologyMalaria Research and ControlTrypanosoma species research and implicationsResearch on Leishmaniasis Studies