Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor
Debanjan Bhattacharjee, Jaweria Bakar, Surbhi P. Chitnis, Erin L. Sausville, Kumar Dilip Ashtekar, Brianna E. Mendelson, Kaitlin Long, Joan C. Smith, David E. Heppner, Jason M. Sheltzer
Topics & Concepts
PotencyPharmacologyChemistryMedicineBiochemistryIn vitroMelanoma and MAPK PathwaysCancer Mechanisms and TherapyCancer-related Molecular Pathways