Antitumour vaccination via the targeted proteolysis of antigens isolated from tumour lysates
Yu Zhao, Donghui Song, Zeyu Wang, Qingqing Huang, Fan Huang, Zhongfeng Ye, Douglas Wich, Mengting Chen, Jennifer Khirallah, Shuliang Gao, Yang Liu, Qiaobing Xu
Topics & Concepts
AntigenAntigen processingAntigen presentationCancer researchEpitopeCytotoxic T cellImmunotherapyImmune systemCross-presentationImmunologyCancer vaccineBiologyCancer immunotherapyMajor histocompatibility complexMHC class IT cellIn vitroBiochemistryImmunotherapy and Immune ResponsesUbiquitin and proteasome pathwaysvaccines and immunoinformatics approaches