Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis
Jason S. Seidman, Ty D. Troutman, Mashito Sakai, Anita Gola, Nathanael J. Spann, Hunter Bennett, Cassi M. Bruni, Zhengyu Ouyang, Rick Z. Li, Xiaoli Sun, Binh T. Vu, Martina P. Pasillas, Kaori M. Ego, David Gosselin, Verena M. Link, Ling-Wa Chong, Ronald M. Evans, Bonne M. Thompson, Jeffrey G. McDonald, Mojgan Hosseini, Joseph L. Witztum, Ronald N. Germain, Christopher K. Glass
Topics & Concepts
BiologyKupffer cellSteatohepatitisEpigeneticsReprogrammingTREM2PhenotypeMacrophageCell biologyTranscriptomeCellImmunologyGene expressionCancer researchFatty liverGeneGeneticsPathologyInflammationMicrogliaMedicineDiseaseIn vitroLiver Disease Diagnosis and TreatmentImmune cells in cancerPhagocytosis and Immune Regulation