Shikonin-mediated PD-L1 degradation suppresses immune evasion in pancreatic cancer by inhibiting NF-κB/STAT3 and NF-κB/CSN5 signaling pathways
Zhiyan Ruan, Minhua Liang, Ling Shang, Manxiang Lai, Xiangliang Deng, Xinguo Su
Topics & Concepts
Immune systemCancer researchPancreatic cancerNF-κBSTAT3In vivoIκBαSignal transductionChemistryMedicineBiologyCell biologyCancerImmunologyInternal medicineBiotechnologyCancer Immunotherapy and BiomarkersTryptophan and brain disordersBioactive Compounds and Antitumor Agents