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DNA methylation disruption reshapes the hematopoietic differentiation landscape

Franco Izzo, Stanley Chun-Wei Lee, Asaf Poran, Ronan Chaligné, Federico Gaiti, Baptiste Gross, Rekha R. Murali, Sunil Deochand, Chelston Ang, Philippa Wyndham Jones, Anna S. Nam, Kyu‐Tae Kim, Steven Kothen-Hill, Rafael Schulman, Michelle Ki, Priscillia Lhoumaud, Jane A. Skok, Aaron D. Viny, Ross L. Levine, Ephraim Kenigsberg, Omar Abdel‐Wahab, Dan A. Landau

2020Nature Genetics256 citationsDOIOpen Access PDF

Topics & Concepts

BiologyDNA methylationEpigeneticsHaematopoiesisMethylationCpG siteStem cellTranscription factorGeneticsProgenitor cellGATA2Cellular differentiationMolecular biologyGeneGene expressionEpigenetics and DNA MethylationAcute Myeloid Leukemia ResearchSingle-cell and spatial transcriptomics
DNA methylation disruption reshapes the hematopoietic differentiation landscape | Litcius