Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma
Risheng Yang, Yuanlin Zhao, Yu Gu, Ying Yang, Xing Gao, Yuan Yuan, Liming Xiao, Jin Zhang, Chao Sun, Han Kwang Yang, Junhui Qin, Jing Li, Feng Zhang, Lijun Zhang, Jing Ye
Topics & Concepts
BiologyIsocitrate dehydrogenaseABCA1Liver X receptorGliomaLDL receptorIDH1CholesterolApolipoprotein EEndocrinologyCancer researchMutantInternal medicineBiochemistryLipoproteinNuclear receptorTransporterTranscription factorEnzymeMedicineDiseaseGeneCholesterol and Lipid MetabolismCancer, Lipids, and MetabolismDrug Transport and Resistance Mechanisms