Pediatric Outcomes After Regulatory Mandates for Sepsis Care
Kristin Hittle Gigli, Billie S. Davis, Jonathan G. Yabes, Chung-Chou H. Chang, Derek C. Angus, Tina Batra Hershey, Jennifer R. Marín, Grant R. Martsolf, Jeremy M. Kahn
Abstract
BACKGROUND: In 2013, New York introduced regulations mandating that hospitals develop pediatric-specific protocols for sepsis recognition and treatment. METHODS: We used hospital discharge data from 2011 to 2015 to compare changes in pediatric sepsis outcomes in New York and 4 control states: Florida, Massachusetts, Maryland, and New Jersey. We examined the effect of the New York regulations on 30-day in-hospital mortality using a comparative interrupted time-series approach, controlling for patient and hospital characteristics and preregulation temporal trends. RESULTS: = .01). CONCLUSIONS: Implementation of statewide sepsis regulations was generally associated with improved mortality trends in New York State, particularly in prespecified subpopulations of patients, suggesting that the regulations were successful in affecting sepsis outcomes.