An Overview on the Role of Xanthine Oxidase Inhibitors in Gout Management
Adnan Ali Alghamdi, Jameel Sami Althumali, M Meshal Mohammed Almalki, Ahmad Saeed Almasoudi, Ali Hussain Almuntashiri, Abdulaziz Hassan Almuntashiri, Alkhrizi Ibrahim Mohammed, Ashraf Ali Alkinani, Meshari Saeed Almahdawi, M Ali Hussain Mahzari
Abstract
Gout is a kind of inflammatory arthropathy that affects a large number of people. Gout and hyperuricemia are becoming more common in developed countries. Xanthine Oxidase (XO) appears to play a key part in excessive uric acid (UA) production. XO inhibitors medications, which reduce serum UA levels by competitive inhibition of XO, are now the medications of choice for the long-term treatment of hyperuricemia. To discuss the role of XO inhibitors in treating gout disease and provide a review of th
Topics & Concepts
Xanthine oxidaseGoutAllopurinolFebuxostatChemistryMedicinePharmacologyBiochemistryInternal medicineEnzymeHyperuricemiaUric acidGout, Hyperuricemia, Uric AcidEosinophilic Disorders and SyndromesPorphyrin Metabolism and Disorders