Clinical Study on Safety and Efficacy of Microwave Ablation for Primary Hyperparathyroidism
Ying Wei, Li-Li Peng, Yan Li, Zhenlong Zhao, Ming-An Yu
Abstract
OBJECTIVE: To evaluate the safety, feasibility, and efficacy of microwave ablation (MWA) for the treatment of primary hyperparathyroidism (PHPT). MATERIALS AND METHODS: This study enrolled 67 PHPT patients (22 men, 45 women; mean age, 56.0 ± 16.3 years; range, 18-83 years) from January 2015 to December 2018. The laboratory data, including the serum intact parathyroid hormone (iPTH), calcium, phosphorus, and alkaline phosphatase (ALP) levels, were evaluated before MWA and again 2 hours, 1 day, 7 days, 1 month, 3 months, 6 months, 12 months, 18 months, and 24 months after. RESULTS: < 0.01). Hoarseness was a major complication in 4 patients (6.0%), but it improved spontaneously within 2-3 months. CONCLUSION: MWA is safe, feasible, and effective for the treatment of PHPT.